[BostonCard]

https://www.nytimes.com/2020/05/05/nyreg...virus.html

Fifteen children in the NY area have been diagnosed with a Kawasaki-like syndrome, possibly linked to COVID-19.  Annual incidence of Kawasaki disease in the US is 20/100,000, which would translate to about 1700 cases a year in a city the size of New York, or about 140 a month.  Thus 15 cases doesn't strike me as all that unusual, though the fifteen only represent severe cases, so there are probably many more out there.

BC

Actually, there are about 20 cases per 100,000 children under 5 years of age. That translates to 3,000 to 4,000 cases in the USA per year. Practically every case of Kawasaki's disease occurs in kids under 5. 

There are about 430,000 children under the age of 5 in NYC. That would translate into 7 cases of Kawasaki's disease per month, 84 cases per year in NYC. I absolutely guarantee you that there are not 140 cases per month in NYC. I've only had 4 cases in my career. And I know Pediatricians who have never seen a case outside of residency. It is rare.

The other issue is that these kids are much sicker than the usual kid with Kawasaki's. Usually, we give them immunoglobulin, the fever is gone in 24-48 hours, we send them home on low dose ASA, and they are fine. Once in a while a patient gets readmitted with recurrent symptoms. They are followed in Cardiology for a while and they cannot get live virus vaccines for 11 months. Multi-organ failure almost never happens. This set of kids is very unusual.

Thank you for the correction.  That makes a lot more sense.

BC

[BostonCard]

https://www.nytimes.com/2020/05/05/nyreg...virus.html

Fifteen children in the NY area have been diagnosed with a Kawasaki-like syndrome, possibly linked to COVID-19.  Annual incidence of Kawasaki disease in the US is 20/100,000, which would translate to about 1700 cases a year in a city the size of New York, or about 140 a month.  Thus 15 cases doesn't strike me as all that unusual, though the fifteen only represent severe cases, so there are probably many more out there.

BC

Actually, there are about 20 cases per 100,000 children under 5 years of age. That translates to 3,000 to 4,000 cases in the USA per year. Practically every case of Kawasaki's disease occurs in kids under 5. 

There are about 430,000 children under the age of 5 in NYC. That would translate into 7 cases of Kawasaki's disease per month, 84 cases per year in NYC. I absolutely guarantee you that there are not 140 cases per month in NYC. I've only had 4 cases in my career. And I know Pediatricians who have never seen a case outside of residency. It is rare.

The other issue is that these kids are much sicker than the usual kid with Kawasaki's. Usually, we give them immunoglobulin, the fever is gone in 24-48 hours, we send them home on low dose ASA, and they are fine. Once in a while a patient gets readmitted with recurrent symptoms. They are followed in Cardiology for a while and they cannot get live virus vaccines for 11 months. Multi-organ failure almost never happens. This set of kids is very unusual.

Thank you for the correction.  That makes a lot more sense.

BC