Chloroquine trials - Printable Version
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RE: Chloroquine trials - BostonCard - 07-09-2020
(07-09-2020, 02:35 AM)magnus Wrote: In other news, the South Dakota governor was hugging Trump Jr's girlfriend a day before the gf was announced as positive. That next evening, the governor apparently took a flight on Air Force one and chatted with Trump Sr without a mask. (She had tested negative before Trump arrived at Mt Rushmore)
https://apnews.com/743c0b135cf849c3c6df312a9d02b9ad
Did WH staff know she had close contact? Seems risky to let her close to the president even with a negative test. Or I wonder now if Trump will start taking hydroxychloroquine, just in case.
Incubation period is too short; it is generally 3 - 14 days, so even if the governor has contacted COVID-19 from Trump Jr's girlfriend, Noem is very unlikely to have been infectious.
BC
RE: Chloroquine trials - magnus - 07-09-2020
Seems like an unnecessary risk in case she's one of the outliers
RE: Chloroquine trials - M T - 07-10-2020
(07-09-2020, 09:03 AM)BostonCard Wrote:I think serial interval (time between the onset of an infector's symptoms and the onset of an infectee's symptoms) might be more relevant.(07-09-2020, 02:35 AM)magnus Wrote: In other news, the South Dakota governor was hugging Trump Jr's girlfriend a day before the gf was announced as positive. That next evening, the governor apparently took a flight on Air Force one and chatted with Trump Sr without a mask. (She had tested negative before Trump arrived at Mt Rushmore)
https://apnews.com/743c0b135cf849c3c6df312a9d02b9ad
Did WH staff know she had close contact? Seems risky to let her close to the president even with a negative test. Or I wonder now if Trump will start taking hydroxychloroquine, just in case.
Incubation period is too short; it is generally 3 - 14 days, so even if the governor has contacted COVID-19 from Trump Jr's girlfriend, Noem is very unlikely to have been infectious.
BC
(I interpret this as being an upper bound on the mean value for how long from exposure to infectious.)
It is shorter than the incubation period, but still 1.5 days seems too short from exposure to infectious.
One unpublished study: 5.29 days (4.72, 5.86).
An earlier letter from the same authors: 3.96 days (3.53, 4.39)
Another unpublished study: 4.56 days (2.69, 6.42) Taiwan; 4.22 days (3.43, 5.01) Tianjin
Another study: 4.6 days (3.5, 5.9)
RE: Chloroquine trials - dabigv13 - 07-10-2020
The White House response continues to be moronic, now trying to strong-arm the FDA into another emergency approval for hydroxychloroquine. Why is Peter Navarro, a trade advisor with no medical training, involved in this at all? Shouldn't he be trying to figure out how we can get more PPE as director of DPA policy?
https://www.washingtonpost.com/health/2020/07/10/peter-navarro-hydroxychloroquine-coronavirus/
RE: Chloroquine trials - BostonCard - 07-23-2020
Another day, another study further throwing cold water on the possibility that hydroxychloroquine ± azithromycin will work for COVID-19. This time in animal models:
https://www.nature.com/articles/s41586-020-2558-4_reference.pdf
Under normal circumstances, this study would have been done first, and then the drug would have been tested in humans.
BC
Two-for-one today.
https://www.nejm.org/doi/full/10.1056/NEJMoa2019014?query=RP
HCQ ± Azithromycin fails to make a difference in patients with mild disease.
Here's the main result
![[Image: nejmoa2019014_f1.jpeg]](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/0/nejm.ahead-of-print/nejmoa2019014/20200723/images/img_xlarge/nejmoa2019014_f1.jpeg)
The "ordinal scale" represents categories of severity ranging from 1 (no need for oxygen and no limitations on activity) to 7 (death). The distribution of the categories is basically the same regardless of treatment.
BC
RE: Chloroquine trials - magnus - 07-26-2020
(07-09-2020, 02:35 AM)magnus Wrote:Bolsonaro has tested negative(07-08-2020, 02:18 AM)magnus Wrote: The Brazilian president said he was using it.Not just said, but advertising his use on social media.
https://apnews.com/66a86e4cccf4e94ea75a8eedd92afeb3
I guess if he recovers, it'll give him that much more proof of its effectiveness and of his stance that the coronavirus is just another flu.
Talk about betting on oneself.
In other news, the South Dakota governor was hugging Trump Jr's girlfriend a day before the gf was announced as positive. That next evening, the governor apparently took a flight on Air Force one and chatted with Trump Sr without a mask. (She had tested negative before Trump arrived at Mt Rushmore)
https://apnews.com/743c0b135cf849c3c6df312a9d02b9ad
Did WH staff know she had close contact? Seems risky to let her close to the president even with a negative test. Or I wonder now if Trump will start taking hydroxychloroquine, just in case.
https://hosted.ap.org/peninsuladailynews/article/47f81f37904d4d3f8fe8e0a1f97ec8b5/brazils-bolsonaro-says-he-tested-negative-coronavirus
RE: Chloroquine trials - BostonCard - 11-09-2020
Allow me to beat a dead horse...
https://jamanetwork.com/journals/jama/fullarticle/2772922?guestAccessKey=39a5ea0f-7853-478d-9f94-6e83c06cc89b&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=110920
BC