Guide to vaccine development - Printable Version

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Guide to vaccine development - BostonCard - 04-29-2020

https://www.nature.com/articles/d41586-020-01221-y

Nature had a great article and set of infographics showing all the different shots on goal that are going on with regard to vaccine development.  Here's the overview of approaches:



The mechanistic figures are great.

BC

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RE: Guide to vaccine development - M T - 04-30-2020

Thanks for that.  I haven't been following vaccine hopes.

One of the studies I've seen indicated that the reintroduced cases of COVID-19 in Wuhan appeared to be less severe than the original cases. 

I can imagine several reasons for that (assuming the effect is real, which I didn't evaluate):
1) Earlier detection of the disease
2) Better prepared health care system
3) Change in the virus affecting its severity
4) More resistance in the people that got the reintroduced cases

#4 is one that could give me hope for a vaccine.  If the population was widely exposed to low levels of the virus (or maybe to inactive virus), then maybe their immune systems were in a better position to blunt the infection or to fight it off..

While we want a vaccine that conveys immunity, I'd be happy for an initial vaccine that reduced lethality by 50%.

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RE: Guide to vaccine development - dabigv13 - 04-30-2020

This was a great visual guide, thanks for posting.

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