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Anticoagulants as a treatment - Printable Version

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Anticoagulants as a treatment - burger - 05-07-2020

Clotting seems to be a big problem for people with the virus . A couple of new articles offer the possibility that anticoagulants might be useful in treating it.  This feels more promising than most treatments I've seen discussed so far.

First is a real published study in a cardiology journal: https://www.eurekalert.org/pub_releases/2020-05/tmsh-btm050420.php
Quote:Treating hospitalized COVID-19 patients with anticoagulants--blood thinners that slow down clotting--may improve their chances of survival, researchers from the Mount Sinai COVID Informatics Center report. The study, published in the May 6 issue of the Journal of the American College of Cardiology, could provide new insight on how to treat and manage coronavirus patients once they are admitted to the hospital.

The study found that hospitalized COVID-19 patients treated with anticoagulants had improved outcomes both in and out of the intensive care unit setting. The research also showed that the difference in bleeding events among patients treated with and without anticoagulants was not significant. The Mount Sinai researchers say their work outlines an important therapeutic pathway for COVID-19 patients.


And a news article in Science reporting some observations: https://science.sciencemag.org/content/368/6490/455

Quote:Negri developed this idea after treating a woman whose breathing troubles coincided with circulatory problems in her toes. Negri's team gave the woman heparin, a common blood thinner, and not only her toes but her breathing recovered. Negri wondered whether heparin could boost patients' low oxygen levels regardless of whether they were struggling to breathe. On 20 April, she posted a preprint detailing her hospital's experience with 27 COVID-19 patients. Patients with hypoxia received heparin, and the dose was increased if they had elevated levels of D-dimer, a blood marker of excess clotting.

One of the 27 was lost to follow-up after transferring to another hospital. But 24 others are recovering—including six of eight who needed mechanical ventilation, a better rate of positive outcomes than has been reported elsewhere. Two remain critically ill. Negri is now planning to follow more patients. And several clinical trials elsewhere will test whether blood thinners can prevent or treat complications of severe COVID-19, including respiratory problems.

Maybe the doctors can weigh in: if you get the virus and are not being treated in a hospital, would it be smart to start taking aspirin?


RE: Anticoagulants as a treatment - dabigv13 - 05-07-2020

Please consult with your primary care doctor before adding any new medication and don't trust strangers on the internet with health advice.

That being said, I personally have started taking an 81mg aspirin tab daily after I read the article on young people with strokes. Who knows if it will help reduce stroke risk from covid, but it makes me feel a little bit better.