04-01-2020, 02:24 PM
(04-01-2020, 01:14 PM)2006alum Wrote: Stuff like this is why I think we should focus less on Chinese numbers and more on working with their scientists - every country in the world is highly incentivized to find effective treatments and eventually preventative care:
[tweet]https://twitter.com/Reuters/status/1245435765456138241?s=20[/tweet]
Now there is concern about ADE (antibody-dependent enhancement).
https://www.sciencedirect.com/science/ar...7920300344
and
https://jvi.asm.org/content/94/5/e02015-19
ADE means that antibodies against other coronavirus actually make infection worse. This is a phenomenon seen with dengue fever; the first case is usually mild, but by the time someone gets infected by a third or fourth strain of dengue it can be deadly. It might also explain the age gradient in severity (older patients are more likely to have been exposed to other coronaviruses). If this is true, the rush to a vaccine, and convalescent serum might wind up being a mistake.
BC
