I think this may be the final version of the study posted at the top of this thread, need to read it more closely. It's a smaller study than the trial being discussed in the WSJ article today. But it's otherwise a decent study, and can't be discounted. If remdesivir was a miracle cure, that would be clear. It's possible remdesivir is helpful. More data will help to distinguish this, and I'd very much welcome being wrong.
Edit:
Yup, this is the same study as posted in the stat news article above.
The most positive thing in the study is that if you got remdesivir within 10 days of symptom onset, the time to improvement was shorter than placebo, but not to a statistically significant degree. Maybe a larger study can get a statistically significant result. Even if true, not a silver bullet.
Edit:
Yup, this is the same study as posted in the stat news article above.
The most positive thing in the study is that if you got remdesivir within 10 days of symptom onset, the time to improvement was shorter than placebo, but not to a statistically significant degree. Maybe a larger study can get a statistically significant result. Even if true, not a silver bullet.
Quote:Although not statistically significant, in patients receiving remdesivir or placebo within 10 days of symptom onset in the ITT population, those receiving remdesivir had a numerically faster time to clinical improvement than those receiving placebo (median 18·0 days [IQR 12·0–28·0] vs 23·0 days [15·0–28·0]; HR 1·52 [0·95–2·43]; appendix p 6