06-20-2020, 04:14 AM
If infection with the disease doesn't confer long term immunity, it's not very likely a vaccine would either.
That being said, just because a robust antibody response isn't always seen after a first exposure doesn't mean a patient wouldn't have some long term immunity. Memory T cells and B cells would mean a second exposure most likely would be less severe than the first.
On ground glass opacities, a small unilateral one is unlikely to have any functional significance. The sort of thing we see not infrequently on a chest CT scan most likely as a sequela of some remote infection, and don't pay much mind too.
Finally, this is a small study, from a single center. 37 patients is not something we should let guide any decision making about this disease. Need more robust studies.
That being said, just because a robust antibody response isn't always seen after a first exposure doesn't mean a patient wouldn't have some long term immunity. Memory T cells and B cells would mean a second exposure most likely would be less severe than the first.
On ground glass opacities, a small unilateral one is unlikely to have any functional significance. The sort of thing we see not infrequently on a chest CT scan most likely as a sequela of some remote infection, and don't pay much mind too.
Finally, this is a small study, from a single center. 37 patients is not something we should let guide any decision making about this disease. Need more robust studies.