[akiddoc]

https://www.medrxiv.org/content/10.1101/...20200048v2

A variety of genetic variants may lead to the abnormal inflammatory reactions in many patients who become very sick.

[akiddoc]

https://www.medrxiv.org/content/10.1101/...20200048v2

A variety of genetic variants may lead to the abnormal inflammatory reactions in many patients who become very sick.

[BostonCard]

In addition to the locus on the ABO blood group, these are interesting.  There's a fair bit of work on the effect of interferon pathway mutations and COVID-19.

https://science.sciencemag.org/content/e...ce.abd4585

Some people have auto antibodies against type I interferons, which are associated with life-threatening COVID-19 infections.

https://science.sciencemag.org/content/e...ce.abd4570

Patients with deficiencies in the type I interferon pathways are also more susceptible to severe COVID-19.

Here's a pretty good summary of the two articles:
https://www.sciencemag.org/news/2020/09/...9-patients

BC

[BostonCard]

In addition to the locus on the ABO blood group, these are interesting.  There's a fair bit of work on the effect of interferon pathway mutations and COVID-19.

https://science.sciencemag.org/content/e...ce.abd4585

Some people have auto antibodies against type I interferons, which are associated with life-threatening COVID-19 infections.

https://science.sciencemag.org/content/e...ce.abd4570

Patients with deficiencies in the type I interferon pathways are also more susceptible to severe COVID-19.

Here's a pretty good summary of the two articles:
https://www.sciencemag.org/news/2020/09/...9-patients

BC